Studies of historical and recorded earthquakes in Palestine demonstration that damaging earthquakes are occurring frequently along the Dead Sea Transform: Earthquake of 11 July 1927 (ML 6.2), earthquake of 11 February 2004(ML 5.2). In order to reduce seismic vulnerability of buildings, losses in lives, properties and infrastructures, and an attempt was made to estimate the percentage of damage degrees and losses at the selected refugee camps: Al Ama’ri, Balata and Dhaishe. Assessing the vulnerability classes of building structure was carried out according to the European Macro-seismic scale 1998(EMS-98) and the Federal Emergency Management Agency (FEMA). The rapid assessment result showed that very heavy structural and non structural damage will occur in the common buildings of the investigated refugee camps (many buildings will suffer from damages grades 4 and 5). Bad quality of buildings in terms of design and construction, lack of uniformity, absence of space between the building and the limited width of roads will definitely increase the seismic vulnerability   under the influence of moderate-strong (M 6-7) earthquake in the future.